Balsamic Vinegar Improves High Fat-Induced Beta Cell Dysfunction via Beta Cell ABCA1

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Balsamic Vinegar Improves High Fat-Induced Beta Cell Dysfunction via Beta Cell ABCA1

BACKGROUND The aim of this study was to investigate the effects of balsamic vinegar on β-cell dysfunction. METHODS In this study, 28-week-old Otsuka Long-Evans Tokushima Fatty (OLETF) rats were fed a normal chow diet or a high-fat diet (HFD) and were provided with tap water or dilute balsamic vinegar for 4 weeks. Oral glucose tolerance tests and histopathological analyses were performed there...

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Response: Balsamic Vinegar Improves High Fat-Induced Beta Cell Dysfunction via Beta Cell ABCA1 (Diabetes Metab J 2012;36:275-9)

Corresponding author: Bong Soo Cha Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Korea E-mail: [email protected] We sincerely appreciate the interest and comments regarding our study, “Balsamic Vinegar Improves High Fat-Induced Beta Cell Dysfunction via Beta Cell ABCA1,” which was published in Diabetes & Metabolism Journal 2012;36...

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Letter: Balsamic Vinegar Improves High Fat-Induced Beta Cell Dysfunction via Beta Cell ABCA1 (Diabetes Metab J 2012;36:275-9)

Corresponding author: Jae-Hyoung Cho Department of Endocrinology and Metabolism, Seoul St. Mary’s Hospital, The Catholic University of Korea School of Medicine, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Korea E-mail: [email protected] It is well known that lipotoxicity can cause β-cells injury and/ or dysfunction as well as glucotoxicity [1-4]. If we could expect improvement of β-cell dy...

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IL-13 improves beta-cell survival and protects against IL-1beta-induced beta-cell death

OBJECTIVES IL-13 is a cytokine classically produced by anti-inflammatory T-helper-2 lymphocytes; it is decreased in the circulation of type 2 diabetic patients and impacts positively on liver and skeletal muscle. Although IL-13 can exert positive effects on beta-cell lines, its impact and mode of action on primary beta-cell function and survival remain largely unexplored. METHODS Beta-cells w...

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Beta Cell Protective Effects of Sodium Tungstate in Streptozotocin-Induced Diabetic Rats: Glycemic Control, Blockage of Oxidative Stress and Beta Cell Histochemistry

Background: Diabetes is a major public health problem. The development of new therapies that are able to improve glycemia management and even to cure diabetes is of great interest. In this study, protective effects of sodium tungstate against STZ-induced beta-cell damages were investigated. Methods: Sixty rats were divided into six groups: control, diabetic, sodium tungstate treated diabetic r...

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ژورنال

عنوان ژورنال: Diabetes & Metabolism Journal

سال: 2012

ISSN: 2233-6079,2233-6087

DOI: 10.4093/dmj.2012.36.4.275